__  __    __   __  _____      _            _          _____ _          _ _ 
 |  \/  |   \ \ / / |  __ \    (_)          | |        / ____| |        | | |
 | \  / |_ __\ V /  | |__) | __ ___   ____ _| |_ ___  | (___ | |__   ___| | |
 | |\/| | '__|> <   |  ___/ '__| \ \ / / _` | __/ _ \  \___ \| '_ \ / _ \ | |
 | |  | | |_ / . \  | |   | |  | |\ V / (_| | ||  __/  ____) | | | |  __/ | |
 |_|  |_|_(_)_/ \_\ |_|   |_|  |_| \_/ \__,_|\__\___| |_____/|_| |_|\___V 2.1
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<HTML>
<HEAD>
<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=windows-1252">
<META NAME="Generator" CONTENT="Microsoft Word 97">
<TITLE>ANTICOLINESTER�SICO</TITLE>
<META NAME="ProgId" CONTENT="FrontPage.Editor.Document">
<META NAME="Template" CONTENT="C:\Arquivos de programas\Microsoft Office\Office\html.dot">
</HEAD>
<BODY LINK="#0000ff" VLINK="#800080" BACKGROUND="../images/fundo1.jpg">

<FONT SIZE=2><P>&nbsp;</P>
</FONT><B><I><FONT FACE="Arial"><P ALIGN="CENTER"><A NAME="_Toc451329665">ANTICOLINESTER&Aacute;SICO</A></P>
</B></I></FONT><FONT SIZE=2><P>&nbsp;</P>
</FONT><FONT FACE="Arial"><P><A NAME="_Toc451329666">TACRINA</A></P>

<UL>
</FONT><B><LI>Indica&ccedil;&otilde;es:</LI></UL>

</B><P ALIGN="JUSTIFY">No tratamento da dem&ecirc;ncia mental (<I>Demencia praecox</I>), &eacute; um inibidor da colinesterase, derivado da acridina , indicado na doen&ccedil;a de Alzheimer.</P>

<UL>
<B><P ALIGN="JUSTIFY"><LI>N&atilde;o deve ser administrado em:</LI></P></UL>

</B><P ALIGN="JUSTIFY">Mulher amamentando; pacientes com hipersensibilidade aos derivados da acridina; pacientes que desenvolveram icter&iacute;cia quando submetidos a tratamento anterior com esse produto.</P>

<UL>
<B><P ALIGN="JUSTIFY"><LI>Deve ser administrado cautelosamente em:</LI></P></UL>

</B><P ALIGN="JUSTIFY">Bradicardia; disfun&ccedil;&atilde;o gastrintestinal; dist&uacute;rbios metab&oacute;licos; doen&ccedil;a gastrintestinal; doen&ccedil;a hep&aacute;tica; doen&ccedil;a de Parkinson; epilepsia; hipotens&atilde;o; hist&oacute;ria de asma ou convuls&otilde;es; les&atilde;o intracraniana; s&iacute;ndrome sinusal; traumatismo craniano com perda da consci&ecirc;ncia; &uacute;lcera p&eacute;ptica.</P>

<UL>
<B><P ALIGN="JUSTIFY"><LI>Efeitos indesej&aacute;veis e/ou rea&ccedil;&otilde;es adversas:</LI></P></UL>

</B><P ALIGN="JUSTIFY">Agita&ccedil;&atilde;o; alucina&ccedil;&atilde;o; ansiedade; ataxia (falta de coordena&ccedil;&atilde;o muscular); aumento da frequ&ecirc;ncia urin&aacute;ria; confus&atilde;o mental; constipa&ccedil;&atilde;o intestinal; depress&atilde;o; diarr&eacute;ia; diminui&ccedil;&atilde;o de peso; diminui&ccedil;&atilde;o dos batimentos card&iacute;acos; dor de cabe&ccedil;a; dor muscular; dor na barriga; dor nas costas; dor no t&oacute;rax; eleva&ccedil;&atilde;o da transaminase; erup&ccedil;&atilde;o na pele; fadiga; falta de apetite; fraqueza; gases; hostilidade; incontin&ecirc;ncia urin&aacute;ria; infec&ccedil;&atilde;o do trato respirat&oacute;rio superior; infec&ccedil;&atilde;o do trato urin&aacute;rio; ins&ocirc;nia; m&aacute; digest&atilde;o; n&aacute;usea; pensamentos anormais; pequenas hemorragias na pele e mucosas; rinite; ruboriza&ccedil;&atilde;o da pele; sonol&ecirc;ncia; tontura; tosse; tremores; v&ocirc;mito.</P>

<UL>
<B><P ALIGN="JUSTIFY"><LI>Intera&ccedil;&otilde;es medicamentosas e/ou alimentares:</LI></P></UL>

</B><P ALIGN="JUSTIFY">� pode ter sua a&ccedil;&atilde;o aumentada por: cimetidina; colin&eacute;rgico; outro inibidor da colinesterase.</P>
<P ALIGN="JUSTIFY">� pode ter sua a&ccedil;&atilde;o diminu&iacute;da por: fumo.</P>
<P ALIGN="JUSTIFY">� pode aumentar o risco de sangramento gastrintestinal com: antiinflamat&oacute;rios n&atilde;o ester&oacute;ides.</P>
<P ALIGN="JUSTIFY">� pode diminuir a a&ccedil;&atilde;o de, ou ter sua a&ccedil;&atilde;o diminu&iacute;da por: anticolin&eacute;rgicos.</P>
<P ALIGN="JUSTIFY">� pode aumentar a a&ccedil;&atilde;o de: teofilina; outro inibidor da colinesterase; succinilcolina.</P>

<UL>
<B><P ALIGN="JUSTIFY"><LI>Cuidados importantes:</LI></P></UL>

</B><P ALIGN="JUSTIFY">� n&atilde;o descontinuar o uso do produto abruptamente.</P>
<P ALIGN="JUSTIFY">� esse produto n&atilde;o cura o mal de Alzheimer. Apenas ajuda a aliviar os sintomas do mesmo.</P>

<UL>
<B><P ALIGN="JUSTIFY"><LI>Efeitos sobre os testes psicol&oacute;gicos: **DEPRESSOR**</LI></P></UL>

</B><P ALIGN="JUSTIFY">&nbsp;</P>
<P ALIGN="JUSTIFY">&nbsp;</P>
<FONT SIZE=2><P>&nbsp;</P></FONT></BODY>
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