__  __    __   __  _____      _            _          _____ _          _ _ 
 |  \/  |   \ \ / / |  __ \    (_)          | |        / ____| |        | | |
 | \  / |_ __\ V /  | |__) | __ ___   ____ _| |_ ___  | (___ | |__   ___| | |
 | |\/| | '__|> <   |  ___/ '__| \ \ / / _` | __/ _ \  \___ \| '_ \ / _ \ | |
 | |  | | |_ / . \  | |   | |  | |\ V / (_| | ||  __/  ____) | | | |  __/ | |
 |_|  |_|_(_)_/ \_\ |_|   |_|  |_| \_/ \__,_|\__\___| |_____/|_| |_|\___V 2.1
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<HTML>
<HEAD>
<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=windows-1252">
<META NAME="Generator" CONTENT="Microsoft Word 97">
<TITLE>ANTIALCO�LICOS</TITLE>
<META NAME="Template" CONTENT="C:\ARQUIVOS DE PROGRAMAS\MICROSOFT OFFICE\OFFICE\HTML.DOT">
</HEAD>
<BODY LINK="#0000ff" VLINK="#800080" BACKGROUND="../images/fundo1.jpg">

<P ALIGN="CENTER"><A NAME="_Toc451329486"></P>
<P><HR></P>
<B><U><P ALIGN="CENTER">[</B></U><A HREF="#_Toc451334585">ANTIALCO&Oacute;LICOS</A><B><U>]</P>
<P ALIGN="CENTER">[</B></U><A HREF="#_Toc451334586">DROGAS PRINCIPAIS</A><B><U>]</P>
</U><P ALIGN="CENTER">[</B><A HREF="#_Toc451334587">DISSULFIRAN</A><B>] [</B><A HREF="#_Toc451334588">METRONIDAZOL</A><B>]</P>
</B><P><HR></P>
<B><FONT FACE="Arial" SIZE=4 COLOR="#ff0000"><P ALIGN="CENTER"><A NAME="_Toc451334585">ANTIALCO&Oacute;LICOS</A></A></P>

<UL>
</FONT><LI>CONCEITO(S):</LI></UL>

<P>Drogas e/ou medicamentos utilizados no tratamento do alcoolismo. N&atilde;o s&atilde;o estes compostos que promover a cura, mas sim a determina&ccedil;&atilde;o do paciente, pois estas drogas apenas auxiliam no condicionamento de avers&atilde;o ao &aacute;lcool, ou seja, fazem com que, atrav&eacute;s de seus efeitos indesej&aacute;veis, o alco&oacute;latra acabe criando um condicionamento aversivo ao &aacute;lcool e deixe de beber mais facilmente.</P>
<P>&nbsp;</P>
<FONT FACE="Arial" SIZE=4 COLOR="#ff0000"><P ALIGN="CENTER"><A NAME="_Toc451334586">DROGAS PRINCIPAIS</A></P>
</B></FONT><FONT SIZE=2><P>&nbsp;</P>
</FONT><P><HR></P>
<B><I><FONT FACE="Arial" COLOR="#ff0000"><P ALIGN="CENTER"><A NAME="_Toc451329488"><A NAME="_Toc451334587">DISSULFIRAN</A></A></P>

<UL>
</I></FONT><LI>NOME(S) COMERCIAL(IS): </B>ANTIETANOL </LI>
<B><LI>Indica&ccedil;&otilde;es:</LI></UL>

</B><P>Inibidor da enzima que metaboliza o &aacute;lcool; inibidor da alde&iacute;do-desidrogenase. Diminuindo-se a a&ccedil;&atilde;o da alde&iacute;do-desidrogenase, o &aacute;lcool que j&aacute; foi metabolizado &agrave; etanalde&iacute;do, n&atilde;o se converte em &aacute;cido ac&eacute;tico e, com isso, os efeitos desagrad&aacute;veis e desconfort&aacute;veis do alde&iacute;do prevalecem sobre o organismo produzindo urtic&aacute;rias, rubores, febre, cefal&eacute;ia, um mal-estar horrendo e generalizado, favorecendo um condicionamento aversivo e auxiliando no tratamento alcoolismo cr&ocirc;nico.</P>

<UL>
<B><LI>N&atilde;o deve ser administrado em:</LI></UL>

</B><P>Altera&ccedil;&otilde;es no EEG; cirrose hep&aacute;tica; convuls&atilde;o; crian&ccedil;a; dano cerebral; depend&ecirc;ncia de drogas; diabetes; insufici&ecirc;ncia hep&aacute;tica; intoxica&ccedil;&atilde;o cr&ocirc;nica; nefrite; oclus&atilde;o coronariana; psicose; severa doen&ccedil;a card&iacute;aca.</P>

<UL>
<B><LI>Deve ser administrado cautelosamente em:</LI></UL>

</B><P>Erup&ccedil;&atilde;o na pele; mulher amamentando; pacientes que tenham tomado recentemente metronidazol, paralde&iacute;do, &aacute;lcool ou prepara&ccedil;&otilde;es contendo &aacute;lcool (como t&ocirc;nicos vitam&iacute;nicos ou xaropes para tosse).</P>

<UL>
<B><LI>Efeitos indesej&aacute;veis e/ou rea&ccedil;&otilde;es adversas:</LI></UL>

</B><P>Ansiedade; arritmia; colapso cardiovascular; confus&atilde;o mental; convuls&atilde;o; cor amarelada na pele e nos olhos; del&iacute;rio; depress&atilde;o respirat&oacute;ria; depress&atilde;o; dermatite acneiforme ou al&eacute;rgica; desmaio; desordem mental; dor articular; dor de cabe&ccedil;a; dor no t&oacute;rax; erup&ccedil;&atilde;o na pele; fadiga; falta de ar; fraqueza; gosto met&aacute;lico ou gosto de alho na boca; hiperventila&ccedil;&atilde;o; hipotens&atilde;o; impot&ecirc;ncia; infarto do mioc&aacute;rdio; insufici&ecirc;ncia card&iacute;aca congestiva aguda; latejamento dolorido da cabe&ccedil;a; n&aacute;usea; neurite &oacute;tica; neurite; palpita&ccedil;&atilde;o; perda da consci&ecirc;ncia e morte; sede; sensa&ccedil;&atilde;o de agulhadas no corpo; sonol&ecirc;ncia; sudorese; vis&atilde;o borrada; v&ocirc;mito em grande quantidade.</P>

<UL>
<LI>Intera&ccedil;&otilde;es medicamentosas e/ou alimentares:</LI></UL>

<P>� aumenta a a&ccedil;&atilde;o de: antidepressivo tric&iacute;clico; benzodiazepina; cafe&iacute;na; hidanto&iacute;na; warfarina.</P>
<P>� sofre ou provoca aumento das rea&ccedil;&otilde;es adversas com: &aacute;lcool; antidepressivo tric&iacute;clico; benzodiazepina; hidanto&iacute;na; isoniazida; metronidazol.</P>

<UL>
<B><LI>Cuidados importantes:</LI></UL>

</B><P>� n&atilde;o ingerir bebida alco&oacute;lica, bem como alimentos que contenham &aacute;lcool (incluindo vinagres e xaropes), bem como n&atilde;o usar lo&ccedil;&otilde;es para barba, perfumes ou outras prepara&ccedil;&otilde;es t&oacute;picas que tenham &aacute;lcool em sua f&oacute;rmula, incluindo produtos para o h&aacute;lito (bochechos e gargarejos).</P>
<P>� n&atilde;o dirigir ve&iacute;culo, nem operar m&aacute;quina perigosa, pois o produto causa sonol&ecirc;ncia.</P>

<UL>
<B><LI>Efeitos sobre os testes psicol&oacute;gicos: **DEPRESSOR**</LI></UL>

</B><P ALIGN="CENTER"><A NAME="_Toc451329489"><A NAME="_Toc451334588"></P>
<P><HR></P>
<B><I><FONT FACE="Arial" COLOR="#ff0000"><P ALIGN="CENTER">METRONIDAZOL</A></A></P>
</B></I></FONT><P>Veja em <A HREF="http://www.antonini.com.br/fcomp/fcomp40.htm#_Toc437684855">Amebicidas</A></P></BODY>
</HTML>

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