__  __    __   __  _____      _            _          _____ _          _ _ 
 |  \/  |   \ \ / / |  __ \    (_)          | |        / ____| |        | | |
 | \  / |_ __\ V /  | |__) | __ ___   ____ _| |_ ___  | (___ | |__   ___| | |
 | |\/| | '__|> <   |  ___/ '__| \ \ / / _` | __/ _ \  \___ \| '_ \ / _ \ | |
 | |  | | |_ / . \  | |   | |  | |\ V / (_| | ||  __/  ____) | | | |  __/ | |
 |_|  |_|_(_)_/ \_\ |_|   |_|  |_| \_/ \__,_|\__\___| |_____/|_| |_|\___V 2.1
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<HTML>
<HEAD>
<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=windows-1252">
<META NAME="Generator" CONTENT="Microsoft Word 97">
<TITLE>ANTAGONISTA DOS ESTROG�NIOS - ANTIESTROG�NIOS</TITLE>
<META NAME="Template" CONTENT="C:\Arquivos de programas\Microsoft Office\Office\html.dot">
</HEAD>
<BODY LINK="#0000ff" VLINK="#800080" BACKGROUND="../images/fundo1.jpg">

<P ALIGN="CENTER"><A NAME="_Toc447807305"><HR></P>
<B><I><FONT FACE="Arial"><P ALIGN="CENTER">ANTAGONISTA DOS ESTROG&Ecirc;NIOS - ANTIESTROG&Ecirc;NIOS</A></P>

<UL>
</I></FONT><LI>CONCEITO(S):</LI></UL>

</B><P>Medicamentos utilizados no bloqueio da secre&ccedil;&atilde;o de estrog&ecirc;nio. Muitos tumores, chamados estr&oacute;genos-dependentes, dependem do estrog&ecirc;nio para se desenvolver e a inibi&ccedil;&atilde;o da secre&ccedil;&atilde;o deste horm&ocirc;nio bloqueia o desenvolvimento do tumor, facilitando a sua remo&ccedil;&atilde;o cir&uacute;rgica e/ou r&aacute;dio/quimioter&aacute;pica. </P>
<FONT FACE="Arial" COLOR="#ff0000"><P ALIGN="CENTER"><A NAME="_Toc447807306">TAMOXIFENO</A></P>

<UL>
</FONT><B><LI>NOME(S) COMERCIAL(IS):</B> NOLVALDEX; TECNOTAX </LI>
<B><LI>Indica&ccedil;&otilde;es:</LI></UL>

</B><P>Antineopl&aacute;sico, antiestrog&ecirc;nico n&atilde;o ester&oacute;ide, especialmente indicado no c&acirc;ncer de mama</P>

<UL>
<B><LI>N&atilde;o deve ser administrado em:</LI></UL>

</B><P>Durante a gravidez e em mulher amamentando.</P>

<UL>
<B><LI>Deve ser administrado cautelosamente em:</LI></UL>

</B><P>Diminui&ccedil;&atilde;o das plaquetas ou dos leuc&oacute;citos no sangue.</P>

<UL>
<B><LI>Efeitos indesej&aacute;veis e/ou rea&ccedil;&otilde;es adversas:</LI></UL>

</B><P>Altera&ccedil;&atilde;o corneana; aumento de c&aacute;lcio no sangue; catarata; coceira vulvar; confus&atilde;o mental; corrimento vaginal; depress&atilde;o; dist&uacute;rbio visual (vis&atilde;o borrada, diminui&ccedil;&atilde;o da acuidade visual); dor de cabe&ccedil;a; dor localizada; dor tempor&aacute;ria nos ossos e nos tumores; erup&ccedil;&atilde;o na pele; falta de apetite; gordura no f&iacute;gado; hepatite; hiperplasia; intoler&acirc;ncia gastrintestinal; n&aacute;usea; ondas de calor; p&oacute;lipos e carcinoma do endom&eacute;trio; problemas na retina; queda de cabelo; reten&ccedil;&atilde;o de l&iacute;quidos; sangramento vaginal; sensibilidade &agrave; luz; tontura; tromboembolia; trombose; tumor ovariano c&iacute;stico; v&ocirc;mito.</P>

<UL>
<B><LI>Intera&ccedil;&otilde;es medicamentosas e/ou alimentares:</LI></UL>

</B><P>� aumenta a a&ccedil;&atilde;o de: anticoagulantes orais.</P>

<UL>
<B><LI>Cuidados importantes:</LI></UL>

</B><P>� avisar o m&eacute;dico caso os v&ocirc;mitos aconte&ccedil;am imediatamente ap&oacute;s a ingest&atilde;o do produto.</P>
<P>� a dor nos ossos e nos tumores &eacute; tempor&aacute;ria e indica que a a&ccedil;&atilde;o do produto est&aacute; se fazendo sentir.</P>
<P>� se o paciente sentir tontura ou confus&atilde;o mental, deve sentar ou deitar por alguns instantes. Levantar lentamente da cama ou da cadeira. Tomar cuidado ao subir ou descer escadas. </P>
<P>� evitar exposi&ccedil;&atilde;o ao sol ou aos raios ultravioleta. Usar roupas que protejam bem o corpo e protetor solar quando sair.</P>
<B><P>Efeitos sobre os testes psicol&oacute;gicos: **DEPRESSOR**</P>
</B><P ALIGN="CENTER"><HR></P>
<B></B></BODY>
</HTML>

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