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<!DOCTYPE html PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN"> <html> <head> <meta http-equiv="content-type" content="text/html; charset=ISO-8859-1"> <title>Do Zimosterol ao Desmosterol</title> <link rel="stylesheet" href="estilo5.css" type="text/css" media="screen"> </head> <body> <div id="container"> <div id="header" title="sitename"> <h1 style="text-align: center;"><img style="width: 800px; height: 120px;" alt="" src="logo.jpg"></h1> </div> <div class="blogentry"> <div style="text-align: center;"><iframe src="indice.html" frameborder="0" height="20" width="800"></iframe></div> <center><font class="option" color="#000000"><b><br> </b></font></center> <br> <h2 style="text-align: center;" class="art-PostHeader"> Do Zimosterol ao Desmosterol </h2> <div><span class="content"><span id="more-2694"></span></span></div> <div style="text-align: center;"> <span class="shutterset_singlepic581"><img style="width: 362px; height: 750px;" class="ngg-singlepic ngg-center" src="../img/zimo-desmo.jpg" alt="Do Zimosterol ao Desmosterol" title="Do Zimosterol ao Desmosterol"></span></div> <div><span class="content"> <p></p> <p style="text-align: justify;">O <strong>ZIMOSTEROL</strong> sofre a ação da enzima Isomerase e converte-se em <strong>D 7,24-COLESTANODIENOL</strong>.</p> </span></div> <span class="content">O <strong>COLESTANODIENOL</strong> sofre uma redução pelo cofator <strong>NADPH<sup>+</sup> + H<sup>+</sup></strong> e transforma-se em <span style="font-weight: bold;">DESMOSTEROL</span>, o precursor imediato do <strong>COLESTEROL. </strong></span>Para se converter em colesterol, o desmosterol recebe um próton <span class="content"><strong>H<sup>+</sup>, </strong></span>rompendo a dupla ligação entre so carbonos da porção trimetil-hepteno (cauda), conforme a reação abaixo:<br> <br> <div style="text-align: center;"><a href="../geral/colesterol_do_desmosterol_ao_colesterol.html"><img style="border: 0px solid ; width: 591px; height: 205px;" alt="Protonação do desmosterol" title="Protonação do desmosterol" src="../img/desmosterol-colesterol.jpg"></a><br> </div> <br> <div style="text-align: right;"> <div style="text-align: right;"><a href="javascript:window.print()"><img style="border: 0px solid ; width: 18px; height: 18px;" alt="Imprimir" title="Imprimir" src="../img/print.png"></a></div> </div> <div style="text-align: center;">[<a href="javascript:history.go(-1)">Voltar</a>]<br> </div> <span style="font-weight: bold;"></span></div> </div> <div id="footer"></div> <br> </body> </html>
